Many years ago, my son, who was 19, was on folic acid. However when he relocated to the United States he was put on hydroxyurea. Soon after he developed a number of symptoms, swollen feed, then seizures.
When he came visiting in Zambia, the haematologist diagnosed a complication where the antibodies were “fighting” against premature red/white blood cells.
The drug was then very new and he felt as a duty to continue to help other patients.
Sadly that took his life.
I cannot say it was drug responsible it may have been other complications.