Fulcrum Therapeutics said it is discontinuing development of pociredir, its experimental oral treatment for sickle cell disease (SCD), after the U.S. Food and Drug Administration (FDA) raised concerns that the therapy may increase the risk of certain blood cancers. The concerns stem from the unexpectedly high rate of…
Higher blood levels of erythropoietin (EPO), a hormone that stimulates the production of red blood cells, increase the risk of blood clot-related, or thrombotic, events in people with sickle cell disease (SCD), according to a study involving more than 500 patients. Researchers also discovered a relationship between the production…
The use of pharmaceutical disease-modifying therapies (pDMTs) has increased in recent years among both children and adults with sickle cell disease (SCD), according to a study analyzing U.S. claims data. Over the same eight-year period, the use of chronic blood transfusion therapy (CBT) has remained low and has…
Discussion
Over the past month, Nigeria, where I live, has witnessed several painful losses. One that shook many people was the death of a popular actor, reportedly due to metastatic kidney cancer. News of his death spread quickly across the entertainment industry and on social media. Many Nigerians admired him for…
Becoming educated and informed about sickle cell disease is a good first step. Here you’ll find general information about the disease, including diagnosis, symptoms, and causes.
It helps to know others have been where you are now. Here’s a collection of our columnists’ words of wisdom to help you along on your sickle cell disease journey.
A stem cell transplant is the only potential cure for sickle cell disease, but there are a variety of other treatment approaches. Here you can find more information about current treatments as well as experimental therapies in the pipeline.
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