I recently asked myself a simple question: What does it really mean to live well with sickle cell disease (SCD)? Can someone with a severe, lifelong condition genuinely say they are living well? After reflecting on my journey, I realized that living well has little to do with having…
Discussion
Agios Pharmaceuticals is discontinuing development of its oral therapy candidate, tebapivat, for people with sickle cell disease (SCD). The decision follows results from a small Phase 2 clinical trial (NCT06924970) showing that while tebapivat — an activator of the pyruvate kinase (PK) enzyme — reduced measures of red…
Discussion
As both a physician and someone living with sickle cell disease (SCD), I spend a great deal of time reading SCD-related medical literature. Recently, while reviewing several publications, both old and recent, on vaso-occlusive crises, I noticed recurring statements that made me pause: Acute sickle cell pain and vaso-occlusive…
Discussion
In the U.S., doctors who care for people with sickle cell disease (SCD) often don’t have a clear understanding of what motivates patients to participate in clinical trials, according to a survey-based study called LISTEN. Based on the findings, researchers offered a range of suggestions for how doctors can…
Becoming educated and informed about sickle cell disease is a good first step. Here you’ll find general information about the disease, including diagnosis, symptoms, and causes.
It helps to know others have been where you are now. Here’s a collection of our columnists’ words of wisdom to help you along on your sickle cell disease journey.
A stem cell transplant is the only potential cure for sickle cell disease, but there are a variety of other treatment approaches. Here you can find more information about current treatments as well as experimental therapies in the pipeline.
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