One of the $3 million 2026 Breakthrough Prizes — in Life Sciences — has been awarded to two researchers whose discoveries reshaped the treatment of sickle cell disease (SCD). The award from the Breakthrough Prize Foundation, which counts its mission as “honoring scientists as heroes of our society,” is…
A global, late-stage clinical trial testing etavopivat in people with sickle cell disease (SCD) has hit its main goals, showing that the experimental oral therapy improved hemoglobin levels and reduced the risk of painful episodes compared with a placebo. Based on these positive results from the Phase 3…
Discussion
I have often found that my experiences with sickle beta-zero thalassemia make me more resilient. I will recover from a weeklong hospital stay feeling stronger for beating the pain, and leave a doctor appointment feeling proud about how well I am adhering to my medications. But after my most…
People with sickle cell disease (SCD) who live in sub-Saharan Africa are less likely than those in other countries to use common medications to manage the condition, including over-the-counter pain-relieving medicines, a study found. These patients also tended to report a lower perceived disease burden than those in high-income…
Becoming educated and informed about sickle cell disease is a good first step. Here you’ll find general information about the disease, including diagnosis, symptoms, and causes.
It helps to know others have been where you are now. Here’s a collection of our columnists’ words of wisdom to help you along on your sickle cell disease journey.
A stem cell transplant is the only potential cure for sickle cell disease, but there are a variety of other treatment approaches. Here you can find more information about current treatments as well as experimental therapies in the pipeline.
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