Blood levels of heme oxygenase-1, or HO-1, an enzyme that helps protect cells from certain types of damage, are elevated…
Articles by Lindsey Shapiro, PhD
The U.S. Patent Office has given AB Science notice that it will allow a patent to be issued covering the…
Most people with sickle cell disease (SCD) who received a new type of stem cell transplant in a…
A hematopoietic stem cell transplant (HCT) may be a feasible treatment option for adolescents and adults with severe sickle cell…
Fulcrum Therapeutics is planning to report, by midyear, new data from the ongoing PIONEER Phase 1b clinical trial that’s…
In a Phase 1/2 clinical trial, the gene-editing stem cell therapy BEAM-101 worked as intended, and showed early signs of…
Enlargement of the left atrium, one of the heart’s upper chambers, is associated with a greater sickle cell disease…
People with sickle cell trait (SCT), those who carry a mutation in one copy of the HBB gene but do…
A Massachusetts scientist has been awarded the seventh annual Trailblazer Prize for Clinician-Scientists by the Foundation for the National Institutes…
Seeking treatment for acute bouts of pain in hospitals and urgent care clinics is a significant source of distress for…