News

Pfizer has voluntarily withdrawn Oxbryta (voxelotor), a conditionally approved oral therapy for sickle cell disease (SCD), from worldwide markets, saying clinical data shows the treatment’s benefit “no longer outweighs the risk.” Citing an imbalance in vaso-occlusive crises (VOCs) and deaths occurring in patients given Oxbryta in postmarketing…

A Nigerian hematologist will pursue a PhD in health policy at the University of Tennessee Health Science Center to help advance her work on programs for sickle cell disease (SCD) in her home country. Aisha Galadanci Akilu, MD, helped implement a newborn screening program in Kano City, Nigeria, which…

Sigma Gamma Rho Sorority, a national collegiate women’s organization, has committed to raising $2 million by 2028 to support St. Jude Children’s Research Hospital in its efforts to treat children with sickle cell disease (SCD), cancer, and other serious conditions at no cost to their families. The…

People with sickle cell trait (SCT), those who carry a mutation in one copy of the HBB gene but do not have sickle cell disease (SCD), are at an increased risk of blood clots compared with people who don’t carry the trait regardless of racial or ethnic background, according…

One sickle cell disease (SCD) patient may need as many as 50 units of blood and up to 25 units of platelets for the new cell-based gene therapies such as Casgevy and Lyfgenia to be successfully administered, according to the American Red Cross. As a part of…

Using lactated Ringer’s solution instead of normal saline to replace lost fluids in adults admitted to the hospital for vaso-occlusive crises, that is, pain episodes caused by sickle cell disease (SCD), allows for shorter stays, fewer readmissions, and a reduced need for opioids, a study finds.  Dehydrated…

The NewYork-Presbyterian Dalio Center for Health Justice is using basketball to raise awareness about sickle cell disease (SCD). The Sickle Cell Awareness Ball campaign features a special-edition basketball with one crescent-shaped red panel, representing the cell that’s a hallmark feature of the disease. The black-and-red ball is featured…

In the years after undergoing a stem cell transplant, people with sickle cell disease (SCD) exhibit quality-of-life scores that are similar to norms for the general population, according to a recent analysis. “In addition to the well-documented survival benefits of [stem cell transplant] for SCD, this study describes…

Low-intensity stem cell transplants, which use milder conditioning regimens, appear not to damage the lungs and may even improve lung function in adults with sickle cell disease (SCD), according to a new study led by scientists from the National Institutes of Health (NIH). “By using a low-intensity blood…

The sickle cell disease (SCD) community will mark National Sickle Cell Awareness Month through September to help bring greater visibility to the inherited blood disorder and the roughly 100,000 U.S. residents affected by it. The campaign also seeks to raise funds for research and support those with SCD and…