The Japan Agency for Medical Research and Development (AMED) — a national funding agency created to support medical R&D in the Asian nation — has awarded up to $32 million to Epifrontier Therapeutics to advance the clinical development of EPF-001, its investigational therapy for sickle cell disease (SCD)…
News
Through a project aimed at building empathy and understanding among clinicians about sickle cell disease (SCD)-related pain episodes, a team of nurses in Chicago has helped standardize emergency care for these complications and reduce door-to-painkiller time, according to a study. “I set out on this initiative with a very…
A bipartisan team of U.S. senators has introduced legislation to renew funding for a national initiative that connects people with blood disorders such as sickle cell disease (SCD) with unrelated donors for stem cell transplants. If the legislation passes, the national initiative, known as the C.W. Bill Young Cell…
Adults with sickle cell disease (SCD) face a substantial risk of stroke, most often in their 30s and 40s, with lasting physical disability and cognitive impairment, a new study reports. Also, despite recommendations, few patients received blood transfusions shortly after stroke, underscoring “significant gaps in acute stroke management,”…
Hematologists-oncologists who specialize in sickle cell disease (SCD) report higher levels of burnout than those not specializing in SCD, even though no differences in grit and resilience were found between the two groups, according to a nationwide U.S. study. The study surveyed more than 150 hematology-oncology doctors, who are…
In the U.S., having sickle cell disease (SCD) continues to place a heavy clinical burden on patients, who often require multiple medications, frequent blood transfusions, and the use of opioids to control pain. Most individuals with SCD report high barriers to healthcare, with poor access to treatments and little…
Newborns with sickle cell trait (SCT), meaning they carry a mutation in one copy of the HBB gene but do not have sickle cell disease (SCD), show abnormalities in certain biological markers that can be detected within the first week after birth, a new study reports. Differences were found in markers…
A blood test measuring levels of the protein cystatin C may provide a more reliable way to monitor for kidney problems in children and young adults with sickle cell disease (SCD), a small study suggests. Data showed that commonly used formulas based on creatinine-to-protein ratio, a well-established kidney…
Children with sickle cell disease (SCD) are about seven times more likely to have asthma than their unaffected siblings, with odds increasing with age, according to a study in the U.S. These findings highlight the importance of more frequent screening to protect the lungs and prevent asthma-related complications in…
A high dose of pociredir, Fulcrum Therapeutics’ oral drug candidate for sickle cell disease (SCD), boosted fetal hemoglobin (HbF) levels and reduced red blood cell destruction — thereby easing symptoms of anemia — in a small group of patients with the blood disorder. These are the latest results…
Recent Posts
- Japanese agency awards $32M to advance sickle cell treatment to trials
- Intentional lifestyle changes got me through winter without a crisis
- Chicago nurses lead charge to speed up SCD emergency care: Study
- Recognizing the warning signs and symptoms of a sickle cell crisis
- US senators seek 5 more years of federal funding for stem cell program
- Adults with SCD face high risk of stroke in their 30s and 40s, study finds
- Sickle cell doctors face higher burnout than other specialists: Study
- Disease burden heavy for SCD patients in US, despite promise of gene therapy
- The conversation we avoid: Telling children they have sickle cell disease
- New study finds distinct molecular signatures in newborns with SCT