1 Possible Cause Ruled Out for Increased Blood Cancer Risk in SCD

Researchers have ruled out a phenomenon called clonal hematopoiesis as the potential cause of the increased risk of blood cancer in people with sickle cell disease (SCD) by analyzing the genetic data of more than 3,000 SCD patients and 71,000 unaffected people. In clonal hematopoiesis, people acquire mutations that cause…

Gene Therapy LentiGlobin Unlikely Cause of Blood Cancer in Early Trial, Bluebird Says

LentiGlobin, Bluebird Bio’s investigational gene therapy for sickle cell disease (SCD), is unlikely to be the cause of a blood cancer that arose in one of the patients who received the therapy in an early clinical trial, according to new analyses. In February, Bluebird paused two clinical…