Posts by: Patricia Inacio, PhD

Patricia Inacio, PhD

Patricia holds her Ph.D. in Cell Biology from University Nova de Lisboa, and has served as an author on several research projects and fellowships, as well as major grant applications for European Agencies. She also served as a PhD student research assistant in the Laboratory of Doctor David A. Fidock, Department of Microbiology & Immunology, Columbia University, New York.

May 21, 2020May 21, 2020

Partnership to Ensure Supply of LentiGlobin, Potential Gene Therapy

News

Bluebird Bio extended a partnership with two divisions of Hitachi Chemical for the long-term development and manufacturing of LentiGlobin, its investigational gene therapy for sickle cell disease (SCD), and other potential and approved treatments. The ... Read more

April 14, 2020April 14, 2020

Phase 2 Trial of Olinciguat, Oral Sickle Cell Therapy, Completely Enrolled

News

The Phase 2 STRONG-SCD trial evaluating olinciguat as a potential oral therapy for sickle cell disease is completely enrolled, Cyclerion Therapeutics said. Seventy patients with stable disease were recruited, ... Read more

April 7, 2020April 7, 2020

GBT Donating $250,000 to Nonprofits Aiding Sickle Cell Community

News

Global Blood Therapeutics (GBT) is giving $250,000 to support the U.S. sickle cell disease (SCD) community during the COVID-19 pandemic. Its newly created GBT Community Fund will award a total ... Read more

March 31, 2020March 31, 2020

Inflammation Markers Identify Sickle Cell Patients at Risk for Worse Outcomes, Study Suggests

News

High blood levels of two pro-inflammatory molecules, called interleukin-6 (IL-6) and interleukin-8 (IL-8), are linked to more frequent complications in people with sickle cell anemia, a study reports. The ... Read more

March 19, 2020March 19, 2020

Approved SCD Therapies Too Costly, ICER Watchdog Group Says

News

The Institute for Clinical and Economic Review (ICER) says three recently approved therapies for managing sickle cell disease (SCD) are too costly based on early assessments of their effectiveness, ... Read more

March 10, 2020March 10, 2020

Pediatric Rare Disease Therapies Increase, But Most Repurposed, Study Finds

News

The number of treatments for children with rare diseases has grown over the past decade, according to a new study. However, despite the increase, nearly 7,000 rare diseases are still ... Read more

November 5, 2019November 5, 2019

Inflammation in Airways of Sickle Cell Children Distinct from Asthma Alone, Pilot Study Suggests

News

White blood cells, especially monocytes, may underlie the breathing difficulties affecting children with sickle cell disease (SCD), a small pilot study suggests. Asthma is estimated to impact from 17% ... Read more

October 31, 2019October 31, 2019

NIH and Gates Foundation Each Invests $100M to Boost Development of Affordable Gene Therapies for Sickle Cell Disease, HIV

News

The National Institutes of Health (NIH) and the Bill & Melinda Gates Foundation will each invest $100 million over the next four years to speed the development of affordable ... Read more

October 29, 2019October 29, 2019

Enhanced Parenting Skills May Help Improve Cognitive Function in SCD Children, Study Suggests

News

Enhanced parenting skills, including attentive listening and engaging in conversations, may help improve cognitive functioning in children with sickle cell disease (SCD), a study suggests. Parent stress was related ... Read more

October 24, 2019October 24, 2019

Caraphenol A May Facilitate Faster, More Effective Gene Therapies for Sickle Cell Anemia, Study Says

News

Caraphenol A — a small molecule closely related to a natural compound called resveratrol, which is produced by red grapes — increased the efficacy of hematopoietic stem cell-based gene ... Read more