The Phase 3 RESET trial testing the effectiveness and safety of rivipansel (GMI-1070), Pfizer‘s investigational candidate to treat vaso-occlusive crisis…
Articles by Patricia Inácio, PhD
Children with sickle cell disease, like adults, have a distinct group of immune cells, called innate like T-cells, that…
A non-invasive prenatal test to diagnose a risk of sickle cell disease in a baby is possible and may be…
Treatment with hydroxyurea since early infancy, starting at the age of one, is effective and safe at preventing sickle…
Imara’s investigational oral inhibitor IMR-687 is well-tolerated, and shows signs of potential for lowering blood biomarkers of…
The Phase 2 STRONG-SCD clinical trial evaluating olinciguat as an investigational therapy for sickle cell disease is seeking participants. Olinciguat,…
Adults with sickle cell disease score worse than their healthy, unaffected siblings on cognitive tests, despite treatment with…
The success rate of bone marrow transplants for patients with sickle cell disease or beta thalassemia, from only “half-matched” donors,…
A Phase 1/2 clinical trial evaluating investigational therapy CTX001 for severe sickle cell disease (SCD) has enrolled its first patient in…
Sickle cell disease (SCD) patients were safely treated with a phosphodiesterase 9A (PDE9) inhibitor therapy called PF-04447943 with no serious…