News

Most women and girls with sickle cell disease (SCD) experience disease-related pain during menstrual periods, but many are unaware that medical treatments — such as birth control pills — may help alleviate period-related pain in SCD, according to a new study by U.S. researchers. Based on these findings, the…

A small clinical trial testing Agios Pharmaceuticals’ oral therapy candidate tebapivat against a placebo for easing symptoms in people with sickle cell disease (SCD) has completed enrollment, the company announced. Agios expects to report early results from the Phase 2 trial later this year, according to a…

The Food and Drug Administration (FDA) has granted breakthrough device designation to the Gazelle Hb Variant test, a point-of-care blood test developed by Hemex Health to enable rapid, low-cost diagnosis of sickle cell disease (SCD) and beta thalassemia. The designation is…

Testing blood levels of certain clotting proteins may help clinicians identify serious complications of sickle cell disease (SCD) in children, a study showed, a finding that could be especially useful in resource-poor settings. Data indicated that vaso-occlusive crises (VOCs) in children with SCD were associated with elevated levels…

Chronic pain among adolescents and young adults with sickle cell disease (SCD) is associated with more functional disability — meaning patients are less able to independently perform daily activities such as bathing, dressing, eating, or working — as well as lower health-related quality of life, according to a new…

A neurodevelopmental screening tool may identify toddlers and preschool children with sickle cell disease (SCD) who are at risk for long-term academic difficulties, a study shows. The tool, called the Ages and Stages Questionnaire (ASQ), is based on parent-reported acquisition of developmental milestones across fine and gross motor…

Researchers from the University of Illinois Chicago (UIC) have received $3.78 million in federal funding to evaluate whether a diabetes medication can slow kidney damage in people with sickle cell disease (SCD). People with SCD face a higher likelihood of developing chronic kidney disease and often lose kidney…