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Link Found in Iron Overload with Sickle Cell Disease, Genetic Mutations

A study performed by researchers at Baskent University, in Ankara, Turkey, found that mutations in certain genes play a role in the deposition of iron in the liver of patients with sickle cell (SC) disease. Findings, presented in the study “Effect of Hereditary Hemochromatosis Gene (HFE)…

Acetylon Pharmaceuticals Publishes Mechanism Of Its Selective-Inhibition Treatment Of Sickle Cell Disease and Beta-Thalassemia

Acetylon Pharmaceuticals recently published the outcomes of its preclinical data concerning the mechanism of action of its selective inhibition based treatment of sickle cell (SC) disease/beta-thalassemia (BT). These findings, “Chemical Inhibition of Histone Deacetylases 1 and 2 Induces Fetal Hemoglobin through Activation of GATA2,” were published in…