A novel nontoxic transplantation method using antibodies proves safe and effective in treating blood diseases, including sickle cell anemia, according to new research. The study, “Non-genotoxic conditioning for hematopoietic stem cell transplantation using a hematopoietic-cell-specific internalizing immunotoxin,” was published in the journal Nature Biotechnology. Patients with blood disorders,…
News
Researchers at the Emory University School of Medicine examined the effects of protective parenting and parent catastrophizing in the quality of life and functional disability of adolescents dealing with chronic pain associated with sickle cell anemia. Catastophizing refers to over protective parenting that sometimes inteferes with a maturing child’s social, developmental and…
Global Blood Therapeutics, a biopharma focused on the development of innovative therapeutics for the treatment of blood-based disorders such as sickle cell disease (SCD), will host an investor’s webcast at 1:30 p.m. June 10. The event will feature members of GBT’s management team and experts during a review of…
A Brazilian study of the relationship between sickle cell anemia (SCA) and endodontic disease indicated that SCA patients in need of a root canal are at risk of infections that stimulate the immune system. The findings highlight the need for government polices to improve dental care for these patients. The study, “Sickle cell anemia in Brazil: personal,…
This week the National Institutes of Health awarded a $2.3 million grant to The New York Blood Center’s (NYBC), one of the largest independent, community-based blood centers in the country, to study potential solutions to abnormal immunologic responses to blood transfusions in patients with sickle cell disease (SCD). The…
A new research study has determined that body measurements (anthropometric variables) of children with sickle cell anemia are usually smaller than healthy children. The research study, “Body mass index and other anthropometric variables in children with sickle cell anemia,” was published in Pakistan Journal of Medical Sciences. Sickle…
A study by researchers at the Hospital for Sick Children, Toronto reveals that the drug hydroxyurea can benefit children with sickle cell (SC) disease related lung problems. The study, “Effect of Hydroxyurea on Pulmonary Function Decline in Children with Sickle Cell Disease,” was presented at the ATS 2016 International…
A group of interdisciplinary researchers from universities and medical colleges in Lagos, Nigeria, recently published a study in the Italian Journal of Pediatrics that has significant public health implications on treating children with sickle cell anemia (SCA) in the developing world. The study, “…
A recently published study in the Journal of Clinical Investigation identified an association between worsening intravascular hemolysis (rupture or destruction of red blood cells) and the rapid clinical deterioration seen during adult transition in Sickle cell disease (SCD). The study, “Nonhematopoietic Nrf2 dominantly…
Sickle cell anemia (SCA), one of the most common hemoglobinopathies, is caused by a mutation in the β-globin gene. In a new research study, the hemorheological and hematological parameters in men suffering from SCA and priapism — a persistent and potentially painful state of penile erection — were investigated.
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