News

Researchers believe that activating a specific oxidative stress regulator with sulforaphane (SFN), a chemical compound found in vegetables such as broccoli and brussels sprouts, might have a therapeutic benefit in patients with sickle cell disease (SCD). They tested their hypothesis in a Phase 1 study that evaluated broccoli sprout homogenate (BSH), which naturally contains SFN,…

The Embrace Kids Foundation has committed $70,000 to support the expansion of Rutgers Robert Wood Johnson Medical School (RWJMS) Comprehensive Sickle Cell Center at Rutgers Cancer Institute of New Jersey (CINJ) to include a pediatric sickle cell and hemoglobinopathies nurse navigator position. The main focus of the new position is…

The American Red Cross and Sports Clips Haircuts have partnered to increase blood and platelet donations across the U.S., offering a coupon for a free haircut to all those who donate during September. Blood donations can be life-saving for people with chronic conditions like sickle cell disease (SCD). “The Red Cross and Sport…

Emmaus Life Sciences announced that expects to submit a New Drug Application (NDA) to the U.S. Food and Drug Administration (FDA) next month for its lead investigational treatment for sickle cell disease. Emmaus’ lead candidate is an oral pharmaceutical grade L-glutamine treatment that demonstrated positive clinical results in…

The William E. Proudford Sickle Cell Fund in celebration of September’s National Sickle Cell Awareness Month is recognizing the accomplishments of Dr. Gary Gibbons, Director of the National Heart, Lung, and Blood Institute (NHLBI). “Under the leadership of Dr. Gibbons, NHLBI has demonstrated…

In sickle cell anemia (SCA), infection with the erythrovirus B19 (B19V) is known to cause transient aplastic crises, in which  production of red blood cells (RBCs) in the bone marrow fails. In this study, researchers describe the clinical course and lab tests of two brothers with sickle cell disease who had the infection.

Researchers developed a mobile app to provide primary care physicians (PCPs) with tools — guidelines, algorithms, and a pathway — needed to communicate effectively with local specialists regarding sickle cell disease. The team from Duke University and the University of Pittsburgh developed the iOS-based ‘toolkit’ after finding that not all…

Pain is an important, and difficult to treat, feature of sickle cell anemia (SCA). Here, researchers compared two different types of mouse models of the disease to study pain and the effects of age and gender on pain development and behaviors. The study highlights how these animal models can increase understanding…

Increasing evidence points to the development of  cardiopulmonary complications in sickle cell anemia (SCA) that may lead to sudden death but cannot be solely attributed to the chronic anemia aspect of the disease. Here, researchers used SCA mouse models to study the physiological, molecular, and cardiac phenotype associated with SCA,…

Early diagnosis of infants affected by sickle cell disease (SCD) through neonatal screening and adequate follow-up are effective tools to decrease the mortality rate associated with the condition. Researchers in central India sought to establish a neonatal screening program and describe the clinical course and hematological presentation of babies with sickle cell.